5 Ways Climb Can Improve your in vivo Research Efficiency

A blog article by Ashlie Reker, PhD., and Ben Wyman, M.A.

1. Accurate, Harmonized Data

Collecting and analyzing data is the reason we do science. Whether for the pursuit of pure knowledge or intentionally identifying lead targets for drug discovery, in vivo research is invaluable to these processes. Increased proficiency and accuracy of bioassays and phenotyping output in this space has led to greater quantities and quality of data. “Big data”, for example, requires collaborative efforts by highly trained statisticians to analyze massive data sets to derive meaningful and applicable conclusions.

Climb aggregates and harmonizes data in the secure Azure cloud promoting accurate, and immediate collaboration between all facets of the R&D and drug discovery processes. Intuitive functionality, data locking, and audits allow data to be located and shared as an export or with role-based access to your instance of Climb. Climb makes data management a breeze.

“Our lab conducts high throughput lab animal phenotyping and generates enormous amounts of complex data. We have high-profile research contracts with NIH and with leading edge companies. Reliable and accurate data capture, experimental reproducibility, and process control are crucial to our science.

We tried a large on premises LIMS, and it failed to meet our need to share data across multiple sites. RockStep Solutions stepped up to the plate with Climb, and their expert data wrangler team worked directly with our phenotyping team to help address our needs.

Our lab now runs more efficiently, and we are getting more science done!”

– Gary Churchill

PhD Professor, Karl Gunnar Johansson Chair, The Jackson Laboratory

2. Better Lab Efficiency

Research studies are rarely, if ever, conducted in isolation, necessitating comprehensive in vivo research management to keep up with the ever-increasing pace of drug discovery. Climb is species-agnostic and customizable for use in any research discipline, such as oncology, neuro, or rare diseases.

Within one secure solution, you can manage your animal colony, design experiments, assign tasks, collect data, and manage samples. As a native cloud solution, Climb is especially advantageous for Clinical Research Organizations that need to get data to clients as soon as possible.

“Adopting Climb has improved our lab’s efficiency and makes it possible to simultaneously manage multiple experiments, coordinate resources, and conduct complex protocols. In addition to having a great product, their support team is fantastic. Climb is clearly a leader in lab animal management systems!”

– Ron Korstanje

PhD FAHA Assistant Professor, The Jackson Laboratory

LIMS

3.  Improved Animal Records and Welfare

One of the greatest challenges for researchers has historically been their ability, or lack thereof, to sufficiently document the health and experimental processes associated with an animal. The use of spreadsheets, notebooks, or even sticky notes to track clinical diagnoses, treatments, and tests, has cost valuable time as technicians scramble to record and later compile regulatory reports. This inefficiency can lead to unwanted animal welfare outcomes and places unnecessary stress on both animals and staff.

Climb easily tracks animal health records and their associated studies and procedures. Our clinical observations capabilities allow vet staff to receive urgent alerts to the internal message system, email, and SMS so treatments can be administered as quickly as possible. Filter and search capabilities make finding this information easy, helping to facilitate IACUC reporting and review as well as adherence to the core principles of animal welfare: reduction, refinement, and replacement.

“I just want to share my positive experience with you about Climb. Prior to using Climb, it was difficult to keep a perfect record on animal usage. It was always a pain when it comes to dealing with IACUC reviews.

 Since we started using Climb a year ago, we have had no mistakes in keeping records, and data entry is a breeze. During our protocol annual review a short while ago, IACUC had zero questions on our animal usage! Thank you!”

– Mu Yang

PhD Director, Mouse NeuroBehavior Core, Institute for Genomic Medicine, Columbia University Medical Center

4. Secure, Easily Accessible Data

Climb helps future-proof your research. Cloud infrastructure frees you from the expensive and disruptive requirements of on-premise servers and maintaining compatibility with outdated legacy point solutions. Climb is browser-based and accessible anywhere for easy, fast collaboration across lab sites and a complete 360 degree view into lab operations.

Data security is critical to successful therapeutics development. Climb is hosted in the Azure cloud, which provides the most comprehensive set of compliance offerings (including certifications and attestations) of any cloud service provider, Data is backed up using real-time replication across geographical zones and can be restored in the event of a disaster or unexpected disruption.

“A big positive for us is that Climb is web based.  We can open it on a home computer or in the mouse room.  Previous databases kept all our information on one computer, and with Climb, we don’t worry about out colony data getting lost if something happens to the computer.  It’s always available.”

 – Julie Siegenthaler

Assistant Professor, Department of Pediatrics, University of Colorado Denver

5. Excellent Customer Support and Training

Here at RockStep, our entire team is committed to providing excellence in both the quality of our product and the experience we provide our customers. We will work with you to configure Climb to best suit your workflows and help your lab get the most out of the platform. User experts can be contacted directly from within the system so there’s no need to switch between email and Climb.

Our team is always considering customer suggestions to improve Climb’s features and make the end product more user-friendly. We want to support the success of your research and get treatments to market faster!

“Climb is user friendly, and it doesn’t take very long to learn how to use it and there is a lot of support from the company to help with training.  Along those lines, the customer support is awesome!  Anytime we’ve had an issue, the support team is very accommodating and always handles our concerns in a timely manner. 

For example, we wanted customized cage cards and they were great about the design and making the cards available for us to access relatively quickly. We would highly recommend Climb for animal colony management and research laboratories.”

– Julie Siegenthaler

Assistant Professor, Department of Pediatrics, University of Colorado Denver

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